Latent Transforming Growth Factor-β Activation in Mammary Gland
نویسندگان
چکیده
منابع مشابه
Transforming Growth Factor-β Regulator SnoN Modulates Mammary Gland Branching Morphogenesis, Postlactational Involution, and Mammary Tumorigenesis
Authors' A University Medicine Canada Note: Curr of Californi Correspon Cell Biolog CA 94720. berkeley.ed
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SnoN is an important negative regulator of transforming growth factor-beta (TGF-beta) signaling that was originally identified as a transforming oncogene in chicken embryonic fibroblasts. Both pro-oncogenic and antioncogenic activities of SnoN have been reported, but its function in normal epithelial cells has not been defined. In the mouse mammary gland, SnoN is expressed at relatively low lev...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2002
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)61158-3